Mendelian Randomization Boot Camp: A Practical Guide to Study Design and Implementation
The Mendelian Randomization Boot Camp is a two-day intensive combination of seminars and hands-on analytical sessions to provide an overview of the concepts, techniques, packages, data sources, and data analysis methods needed to conduct Mendelian Randomization studies.
This two-day intensive boot camp integrates motivation for Mendelian randomization studies, statistical concepts, genetic considerations, and practical examples to design, implement and interpret a Mendelian randomization analysis. Led by a scientist with several award winning papers on Mendelian randomization combined with extensive expertise in epidemiology, the workshop will integrate seminar lectures with hands-on computer sessions to put concepts into practice. Emphasis will be given to leveraging existing publicly available resources (data, tools and packages) as well as indicating the scope for new studies. The afternoon lab sessions will provide an opportunity to work hands-on with real data. Participants will learn and practice all the steps required for a successful Mendelian randomization analysis using publicly available data, including identifying suitable data sources, data extraction, data alignment, assumption checking and sensitivity analysis.
By the end of this Mendelian Randomization training, participants will be familiar with the following topics:
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Principles of Mendelian Randomization
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Implementation options
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Suitable publicly available data sources
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Data interpretation and handling
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Data analysis
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Sensitivity analysis
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Study design advantages and pitfalls
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Emerging Mendelian randomization techniques
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Use of MR-Base
Investigators at all career stages are welcome to attend, and we particularly encourage trainees and early-stage investigators to participate.
PREREQUISITES AND REQUIREMENTS
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Each participant is required have a working laptop or tablet with video and audio capabilities, and a free, basic RStudio Cloud account. All lab sessions will be done using RStudio Cloud.
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The Boot Camp will use data sets in R/RStudio using the RStudio Cloud platform, therefore it is required that each participant has previous experience using R.
If you have any specific questions about R and R studio in the context of the Mendelian Randomization Boot Camp, please email us.
ADDITIONAL INFORMATION
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Email us at [email protected].
Capacity is limited. Paid registration is required to attend.
