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A tiny mutation on the X chromosome can shape a family’s history.
Passed down from a “carrier” parent to a child, fragile X syndrome is the most common inherited cause of intellectual disability and autism. Further troubling the experience of affected families, many fragile X carriers—once thought unaffected—also suffer from disabling symptoms. Author of The Carriers: What the Fragile X Gene Reveals About Family, Heredity, and Scientific Discovery, Anne Skomorowsky narrates the stories of these families exposing the complex interactions between genes, personality, and family dynamics, while underlining the ethical dilemmas of genetic medicine.
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